Low-pressure chromatography columns, in sizes 300 to 1600 mm internal diameter (i.d.), offer automated column packing for process development or manufacturing. Preprogrammed packing methods improve accuracy and ease of use.
Overview
Low-pressure chromatography columns, in sizes 300 to 1600 mm internal diameter (i.d.), offer automated column packing for process development or manufacturing. Preprogrammed packing methods improve accuracy and ease of use.
Scalable from process development to full-scale production on the same platform.
Intelligent Packing, a feature of AxiChrom Master, enables the automated column packing and delivers verified methods and simplified workflows. Optimized for modern chromatography resins, like Capto and MabSelect SuRe families.
Column tube swing out for easy and convenient access to bed supports and O-rings.
Design enabling easy sanitization with materials recognized for use in GMP environments.
Connect with slurry tank and chromatography system to create a closed system.
Wetted and pressure-retaining parts are traceable and polymers are approved according to USP class VI, 21 CFR 177 and Animal free origin or in compliance with EMEA/410/ Supported with IQ/OQ documentation packages.
Larger sized columns offered through CBS – Customized BioProcess Solutions
Packing Axichrom 300 to 1600 columns
Packing AxiChrom columns is facilitated by the Intelligent Packing methodology, where optimal compression of the bed is achieved by preprogrammed, verified packing methods. In AxiChrom 300 and larger columns, packing is controlled by an ÄKTAprocess system or the AxiChrom master, a separate unit comprising a touch-screen operator interface, a motor drive, and preprogrammed methods that support Intelligent Packing. Preprogrammed methods reduce the need for extensive packing know-how and facilitate scale-up and tech-transfer.
AxiChrom Master
Predictable scale-up
The distribution system within the AxiChrom family is based on a theoretical model to ensure uniform flow through the bed, producing reproducible results over a range of scales.
